Abacavir, lamivudine, and zidovudine
Name: Abacavir, lamivudine, and zidovudine
- Abacavir, lamivudine, and zidovudine side effects
- Abacavir, lamivudine, and zidovudine drug
- Abacavir, lamivudine, and zidovudine effects of abacavir, lamivudine, and zidovudine
- Abacavir, lamivudine, and zidovudine tablet
- Abacavir, lamivudine, and zidovudine dosage
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Uses For abacavir, lamivudine, and zidovudine
Abacavir, lamivudine, and zidovudine combination is used alone or together with other medicines to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
Abacavir, lamivudine, and zidovudine combination will not cure or prevent HIV infection or the symptoms of AIDS. abacavir, lamivudine, and zidovudine helps keep HIV from reproducing, and appears to slow down the destruction of the immune system. This may help delay the development of serious health problems usually related to AIDS or HIV infection. Abacavir, lamivudine, and zidovudine combination will not keep you from spreading HIV to other people. People who receive abacavir, lamivudine, and zidovudine may continue to have other problems usually related to AIDS or HIV infection.
abacavir, lamivudine, and zidovudine is available only with your doctor's prescription.
Before Using abacavir, lamivudine, and zidovudine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For abacavir, lamivudine, and zidovudine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to abacavir, lamivudine, and zidovudine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Abacavir, lamivudine, and zidovudine combination contains a fixed amount of each medicine that cannot be decreased. Therefore, abacavir, lamivudine, and zidovudine is not recommended for patients who weigh less than 40 kilograms because the amounts of abacavir, lamivudine, and zidovudine in this product cannot be adjusted for smaller body sizes.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of abacavir, lamivudine, and zidovudine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving abacavir, lamivudine, and zidovudine.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking abacavir, lamivudine, and zidovudine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using abacavir, lamivudine, and zidovudine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Doxorubicin Hydrochloride Liposome
- Vincristine Sulfate Liposome
Using abacavir, lamivudine, and zidovudine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Interferon Beta-1a
- Valproic Acid
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of abacavir, lamivudine, and zidovudine. Make sure you tell your doctor if you have any other medical problems, especially:
- Blood problems (eg, anemia, neutropenia) or
- Diabetes or
- Heart attack, history of or
- Heart disease or
- Hepatitis B, history of or
- Hepatitis C, history of or
- Hyperlipidemia (high cholesterol or fats in the blood) or
- Hypertension (high blood pressure) or
- Myopathy (muscle weakness)—Use with caution. May make these conditions worse.
- Genetic condition (eg, gene variation called HLA-B*5701)—This condition may increase the risk for serious and life-threatening side effects.
- Kidney disease, severe or
- Liver disease, moderate or severe—Should not be used in patients with these conditions.
What are some other side effects of Abacavir, Lamivudine, and Zidovudine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Joint pain.
- Feeling nervous and excitable.
- Feeling tired or weak.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
(a BAK a veer, la MI vyoo deen, & zye DOE vyoo deen)
HIV-1 infection, treatment: Oral: One tablet twice daily.
Dosing Renal Impairment
CrCl ≥50 mL/minute: No dosage adjustment necessary.
CrCl <50 mL/minute: Use is not recommended (use dose-adjusted individual components).
Blood glucose, CBC with differential, serum creatine kinase, CD4 count, HIV RNA plasma levels, bilirubin, serum transaminases, triglycerides, serum amylase; HLA-B*5701 genotype status prior to initiation of therapy and prior to reinitiation of therapy in patients of unknown HLA-B*5701 status; signs and symptoms of hypersensitivity, particularly in patients untested for the HLA-B*5701 allele; signs and symptoms of pancreatitis; observe for appearance of opportunistic infections