Abenol

Name: Abenol

Commonly used brand name(s)

In the U.S.

  • Acephen
  • Actamin Maximum Strength
  • Altenol
  • Aminofen
  • Anacin Aspirin Free
  • Apra
  • Arthritis Pain Relief
  • Cetafen
  • Children's Mapap
  • Children's Nortemp
  • Comtrex Sore Throat Relief
  • Dolono
  • Febrol
  • Feverall
  • Genapap
  • Genebs
  • Infantaire
  • Mapap
  • Mapap Arthritis Pain
  • Pain-Eze +/Rheu-Thritis
  • Pyrecot
  • Pyregesic
  • Q-Pap
  • Redutemp
  • Silapap
  • T-Painol
  • Tycolene
  • Tylenol

In Canada

  • Abenol
  • Acetaminophen
  • Actimol Children's
  • Actimol Infant
  • Atasol
  • Children's Acetaminophen
  • Children's Acetaminophen Bubble Gum Flavor
  • Children's Acetaminophen Cherry Flavor
  • Children's Acetaminophen - Grape
  • Children's Acetaminophen Grape Flavor
  • Children's Acetaminophen Suspension Bubble Gum Flavor - Ages 2 To 11
  • Children's Acetaminophen Suspension Cherry Flavor

Available Dosage Forms:

  • Solution
  • Tablet, Disintegrating
  • Suppository
  • Powder
  • Capsule, Liquid Filled
  • Syrup
  • Tablet
  • Tablet, Chewable
  • Capsule
  • Powder for Solution
  • Suspension
  • Elixir
  • Tablet, Extended Release
  • Liquid
  • Tablet, Effervescent

Therapeutic Class: Analgesic

Renal Dose Adjustments

Severe renal impairment (CrCl less than 30 mL/min): Longer dosing intervals and a reduced total daily dose may be warranted

Liver Dose Adjustments

Parenteral:
Severe hepatic impairment, severe active hepatic disease: Use is contraindicated
Mild to moderate hepatic impairment, mild to moderate active hepatic disease: Use with caution; a reduced total daily dose may be warranted

Over the counter products must contain labeling that states:
This product contains acetaminophen. Severe liver damage may occur if:
-Adult takes more than maximum daily dose in 24 hours
-Child takes more than 5 doses in 24 hours
-More than 3 alcoholic drinks are consumed per day while using this product.

Dose Adjustments

Severe renal impairment (CrCl less than 30 mL/min): Longer dosing intervals and a reduced total daily dose may be warranted

Precautions

US BOXED WARNING: RISK OF MEDICATION ERRORS
Take care when prescribing, preparing, and administering IV acetaminophen injection to avoid dosing errors which could result in accidental overdose and death. In particular, be careful to ensure that
- the dose in milligrams (mg) and milliliters (mL) is not confused;
- the dosing is based on weight for patients under 50 kg;
- infusion pumps are properly programmed;
-the total daily dose of acetaminophen from all sources does not exceed maximum daily limits.

US BOXED WARNING: HEPATOTOXICITY:
This drug has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed the maximum daily limits, and often involve more than 1 acetaminophen-containing product.

US OVER THE COUNTER LABELING: Adults only:
This product contains acetaminophen. Severe liver damage may occur if:
-More than maximum daily dose is taken in 24 hours
-This product is taken with other drugs containing acetaminophen
-Three or more alcoholic drinks are consumer every day while using this product.

US OVER THE COUNTER LABELING: Adults and children under 12 years of age:
This product contains acetaminophen. Severe liver damage may occur if:
-Adult takes more than maximum daily dose in 24 hours
-Child takes more than 5 doses in 24 hours
-This product is taken with other drugs containing acetaminophen
-Persons consume 3 or more alcoholic drinks per day while using this product.

Safety and efficacy for the treatment of acute pain have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

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