Accucaine

Name: Accucaine

Contraindications

Lidocaine is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

How supplied

Lidocaine Hydrochloride Injection, USP is supplied as follows:

NDC

Container

Concentration

Size

Total (mg)

Single-dose:

0409-4278-01

Glass Teartop Vial

0.5% (5 mg/mL)

50 mL

250

0409-4713-01

Glass Ampul

1% (10 mg/mL)

2 mL (bulk – 400 units)

20

0409-4713-02

Glass Ampul

1% (10 mg/mL)

5 mL

50

0409-4713-05

Glass Ampul

1% (10 mg/mL)

5 mL (bulk – 400 units)

50

0409-4713-20

Glass Ampul

1% (10 mg/mL)

20 mL

200

0409-4713-32

Glass Ampul

1% (10 mg/mL)

2 mL

20

0409-4713-62

Glass Ampul

1% (10 mg/mL)

2 mL (bulk – 800 units)

20

0409-4713-65

Glass Ampul

1% (10 mg/mL)

5 mL (bulk – 800 units)

50

0409-4279-02

Glass Teartop Vial

1% (10 mg/mL)

30 mL

300

0409-4270-01

Sterile Glass Teartop Vial

1% (10 mg/mL)

30 mL

300

0409-4776-01

Glass Ampul

1.5% (15 mg/mL)

20 mL

300

0409-4056-01

Sterile Glass Ampul

1.5% (15 mg/mL)

20 mL

300

0409-4282-01

Glass Ampul

2% (20 mg/mL)

2 mL

40

0409-4282-02

Glass Ampul

2% (20 mg/mL)

10 mL

200

Multiple-dose:

0409-4275-01

Plastic Fliptop Vial

0.5% (5 mg/mL)

50 mL

250

0409-4276-01

Plastic Fliptop Vial

1% (10 mg/mL)

20 mL

200

0409-4276-02

Plastic Fliptop Vial

1% (10 mg/mL)

50 mL

500

0409-4277-01

Plastic Fliptop Vial

2% (20 mg/mL)

20 mL

400

0409-4277-02

Plastic Fliptop Vial

2% (20 mg/mL)

50 mL

1000

Single-dose products are preservative-free.

Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.]

Lidocaine Hydrochloride Injection, USP solutions packaged in ampuls and glass teartop vials may be autoclaved one time only. Autoclave at 15 pounds pressure, 121°C (250°F) for 15 minutes. DO NOT AUTOCLAVE PRODUCT IN PLASTIC VIALS.

Revised: February, 2010

Printed in USA                            EN-2421

Hospira, Inc., Lake Forest, IL 60045 USA

For the Consumer

Applies to lidocaine: intradermal powder

Along with its needed effects, lidocaine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking lidocaine:

More common
  • Flushing or redness of the skin
  • itching skin
  • small red or purple spots on the skin
  • unusually warm skin
Less common
  • Bruising, bleeding, burning, swelling, or pain at the application site

Some side effects of lidocaine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Nausea
  • vomiting

Usual Pediatric Dose for Ventricular Tachycardia

The manufacturer gives no specific dosing instructions.

The AHA recommends:
IV:
-Initial dose: 1 mg/kg IV or intraosseous once
-Maintenance infusion: 20 to 50 mcg/kg/min IV

Endotracheal: May be administered endotracheally (bolus dose only) if IV or intraosseous access unavailable at a dose of 2 to 3 times the dose (2 to 3 mg/kg) followed by a flush with at least 5 mL of NS and 5 consecutive positive-pressure ventilations

Use: For use in shock-refractory VF or pVT after resuscitation from cardiac arrest in infants and children

Precautions

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

  • Skin redness, itching, a rash, or a feeling of warmth may occur in the region where lidocaine has been administered subcutaneously when used for local anesthesia. Bruising, bleeding, swelling and pain at the injection site are less common.
  • Side effects may be more severe with lidocaine antiarrhythmic and include lightheadedness, drowsiness, nausea or vomiting, slow heartbeat, and low blood pressure. Drowsiness is usually a reflection of high blood levels of lidocaine.
  • Local anesthetics injected into the head or neck area may produce side effects similar to systemic toxicity including confusion, convulsions, and respiratory depression.
  • IM lidocaine may increase creatine phosphokinase levels which may compromise tests for this enzyme following an acute myocardial infarction.
  • May not be suitable for some people including those with respiratory disease, cardiovascular disease, liver or kidney disease, low blood pressure, epilepsy, myasthenia gravis or congestive heart failure.
  • May interact with some medications including beta-blockers, cimetidine, antiarrhythmics, and HIV agents.

Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects, click here.

Lidocaine Breastfeeding Warnings

During a study in which 26 women were given an epidural of lidocaine 2% and bupivacaine 0.5% for pain control of cesarean deliveries, the average milk concentration of lidocaine reported was 860 mcg/L, 460 mcg/L, and 220 mcg/L at 2, 4, and 12 hours after delivery, respectively.

Caution is recommended. Excreted into human milk: Yes (in small amounts) Comments: Side effects in the nursing infant are unlikely and would probably be limited to an idiosyncratic or allergic reaction.

Lidocaine Identification

Substance Name

Lidocaine

CAS Registry Number

137-58-6

Drug Class

Antiarrhythmics

Local Anesthetics

(web3)