Acetaminophen and dextromethorphan

Name: Acetaminophen and dextromethorphan

What is acetaminophen and dextromethorphan?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Acetaminophen and dextromethorphan is a combination medicine used to treat cough and pain or fever caused by the common cold or flu.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen and dextromethorphan may also be used for purposes not listed in this medication guide.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Acetaminophen and dextromethorphan dosing information

Usual Adult Dose for Cold Symptoms:

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Adult Dose for Cough:

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Adult Dose for Pain:

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Pediatric Dose for Cold Symptoms:

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg oral tablet, chewable:
2 to 5 years: 1 tablet orally, chewed or dissolved before swallowing, every 4 hours not to exceed 5 tablets daily.
6 to 12 years: 2 tablets orally, chewed or dissolved before swallowing, every 4 hours not to exceed 10 tablets daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral liquid:
4 to 5 years: 5 mL orally every 4 hours not to exceed 25 mL daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral suspension:
2 to 5 years: 5 mL orally every 4 hours not to exceed 25 ml daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-7.5 mg/5 mL oral liquid:
2 to 5 years: 5 mL orally every 6 hours not to exceed 20 mL daily.
6 to 12 years: 10 mL orally every 6 hours not to exceed 40 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
6 to 11 years: 1 capsule every 6 hours not to exceed 4 capsules daily.
12 years or older: 1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Pediatric Dose for Cough:

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg oral tablet, chewable:
2 to 5 years: 1 tablet orally, chewed or dissolved before swallowing, every 4 hours not to exceed 5 tablets daily.
6 to 12 years: 2 tablets orally, chewed or dissolved before swallowing, every 4 hours not to exceed 10 tablets daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral liquid:
4 to 5 years: 5 mL orally every 4 hours not to exceed 25 mL daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral suspension:
2 to 5 years: 5 mL orally every 4 hours not to exceed 25 ml daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-7.5 mg/5 mL oral liquid:
2 to 5 years: 5 mL orally every 6 hours not to exceed 20 mL daily.
6 to 12 years: 10 mL orally every 6 hours not to exceed 40 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
6 to 11 years: 1 capsule every 6 hours not to exceed 4 capsules daily.
12 years or older: 1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Pediatric Dose for Pain:

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg oral tablet, chewable:
2 to 5 years: 1 tablet orally, chewed or dissolved before swallowing, every 4 hours not to exceed 5 tablets daily.
6 to 12 years: 2 tablets orally, chewed or dissolved before swallowing, every 4 hours not to exceed 10 tablets daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral liquid:
4 to 5 years: 5 mL orally every 4 hours not to exceed 25 mL daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral suspension:
2 to 5 years: 5 mL orally every 4 hours not to exceed 25 ml daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-7.5 mg/5 mL oral liquid:
2 to 5 years: 5 mL orally every 6 hours not to exceed 20 mL daily.
6 to 12 years: 10 mL orally every 6 hours not to exceed 40 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
6 to 11 years: 1 capsule every 6 hours not to exceed 4 capsules daily.
12 years or older: 1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Adult Dose for Cold Symptoms

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Adult Dose for Cough

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Pediatric Dose for Cough

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg oral tablet, chewable:
2 to 5 years: 1 tablet orally, chewed or dissolved before swallowing, every 4 hours not to exceed 5 tablets daily.
6 to 12 years: 2 tablets orally, chewed or dissolved before swallowing, every 4 hours not to exceed 10 tablets daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral liquid:
4 to 5 years: 5 mL orally every 4 hours not to exceed 25 mL daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral suspension:
2 to 5 years: 5 mL orally every 4 hours not to exceed 25 ml daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-7.5 mg/5 mL oral liquid:
2 to 5 years: 5 mL orally every 6 hours not to exceed 20 mL daily.
6 to 12 years: 10 mL orally every 6 hours not to exceed 40 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
6 to 11 years: 1 capsule every 6 hours not to exceed 4 capsules daily.
12 years or older: 1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Usual Pediatric Dose for Pain

Acetaminophen-dextromethorphan 1000 mg-30 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg oral tablet, chewable:
2 to 5 years: 1 tablet orally, chewed or dissolved before swallowing, every 4 hours not to exceed 5 tablets daily.
6 to 12 years: 2 tablets orally, chewed or dissolved before swallowing, every 4 hours not to exceed 10 tablets daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral liquid:
4 to 5 years: 5 mL orally every 4 hours not to exceed 25 mL daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-5 mg/5 mL oral suspension:
2 to 5 years: 5 mL orally every 4 hours not to exceed 25 ml daily.
6 to 12 years: 10 mL orally every 4 hours not to exceed 50 mL daily.

Acetaminophen-dextromethorphan 160 mg-7.5 mg/5 mL oral liquid:
2 to 5 years: 5 mL orally every 6 hours not to exceed 20 mL daily.
6 to 12 years: 10 mL orally every 6 hours not to exceed 40 mL daily.

Acetaminophen-dextromethorphan 325 mg- 5 mg oral capsule:
6 to 11 years: 1 capsule every 6 hours not to exceed 4 capsules daily.
12 years or older: 1 to 2 capsules orally every 6 hours not to exceed 8 capsules daily.

Liver Dose Adjustments

Use with caution in patients with liver disease. Chronic use of acetaminophen is not recommended in patients with liver disease.

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