Acetohydroxamic acid

Name: Acetohydroxamic acid

Acetohydroxamic Acid Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;
  • signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs; or
  • signs of a red blood cell disorder--pale or yellowed skin, dark colored urine, fever, confusion or weakness.

Common side effects may include:

  • headache during the first 2 days of treatment;
  • skin rash, warmth, tingling or redness (especially if you drink alcohol while taking acetohydroxamic acid);
  • upset stomach, nausea, loss of appetite;
  • depressed mood;
  • anxiety, tremors, nervousness; or
  • hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetohydroxamic acid?

You should not use acetohydroxamic acid if you have kidney disease, or if you have bladder symptoms that have not been checked by a doctor.

This medicine can harm an unborn baby or cause birth defects. Do not use acetohydroxamic acid if you are pregnant or if you are not using birth control.

What should I avoid while taking acetohydroxamic acid?

You may have a skin rash or flushing (warmth, redness, or tingly feeling) if you drink alcohol while taking this medicine.

Ask your doctor before taking any vitamin or mineral supplement that contains iron.

What are some things I need to know or do while I take Acetohydroxamic Acid?

  • Tell all of your health care providers that you take acetohydroxamic acid. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Some people have had a rash with redness, warmth, and tingling after drinking alcohol while taking this medicine. The rash usually happens 30 to 45 minutes after drinking alcohol, and goes away within 30 to 60 minutes. Talk with your doctor before you drink alcohol with acetohydroxamic acid.
  • This medicine may cause harm to the unborn baby if you take it while you are pregnant.
  • Use birth control that you can trust to prevent pregnancy while taking this medicine.
  • If you are pregnant or you get pregnant while taking acetohydroxamic acid, call your doctor right away.

How do I store and/or throw out Acetohydroxamic Acid?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Acetohydroxamic Acid Brand Names

Acetohydroxamic Acid may be found in some form under the following brand names:

  • Lithostat

Usual Pediatric Dose for Urinary Tract Infection

Children with chronic, recalcitrant, urea-splitting urinary infection may benefit from treatment with acetohydroxamic acid. However, detailed studies involving dosage and dose intervals in children have not been established.

Children have tolerated a dose of 10 mg/kg/day, taken in two or three divided doses, satisfactorily for periods up to one year. Therefore, an initial dose of 10 mg/kg/day orally is recommended.

Close monitoring of the patient's clinical condition and hematologic status is recommended. Titration of the dose to higher or lower levels may be required to obtain an optimum therapeutic effect and/or to reduce the risk of side effects.

Liver Dose Adjustments

Data not available

Acetohydroxamic acid Pregnancy Warnings

Acetohydroxamic acid has been assigned to pregnancy category X by the FDA. Animal studies have revealed teratogenicity (retarded and/or clubbed rear leg, exencephaly, and encephalocele). There are no controlled data in human pregnancy. Acetohydroxamic acid is contraindicated in women who are or may become pregnant. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be informed of the potential hazard to the fetus.

Acetohydroxamic acid Breastfeeding Warnings

There are no data on the excretion of acetohydroxamic acid into human milk. Because many drugs are excreted into human milk, and because of the potential for serious adverse reactions in nursing infants from acetohydroxamic acid, a decision should be made to discontinue nursing or the drug, taking into account the significance of the drug to the mother's well being.