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Uses For Adipex
Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants.
This medicine is available only with your doctor's prescription.
Precautions While Using Adipex
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and does not cause any unwanted effects.
Do not use phentermine if you are also using similar medicines such as benzphetamine, diethylpropion, mazindol, phendimetrazine, Bontril®, or Didrex®. Do not use this medicine if you also take an MAO inhibitor (MAOI), such as isocarboxazid (Marplan®), phenelzine (Nardil®,), selegiline (Eldepryl®), or tranylcypromine (Parnate®), or if you have used an MAOI within the past 14 days. Using these medicines together may cause serious unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.
This medicine may be habit-forming. If you think this medicine is not working properly after you have taken it for a few weeks, do not increase the dose. Instead, check with your doctor.
Call your doctor right away if you notice a decrease in your ability to exercise, or if you faint, have chest pain, swelling of your feet or lower legs, or trouble with breathing. These may be symptoms of a very serious heart or lung problem.
This medicine may cause some people to become dizzy, lightheaded, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
This medicine may affect blood sugar levels. Diabetic patients may notice a change in blood or urine sugar tests. Check with your doctor if you have any questions.
Avoid drinking alcohol while you are using this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription and nonprescription (over-the-counter) medicines, dietary supplements, herbal remedies, or medicines for appetite control, asthma, colds, cough, hay fever, and sinus problems.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Methylene Blue
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Agitated state (very nervous or anxious) or
- Arrhythmias (abnormal heart rhythms), history of or
- Arteriosclerosis (hardening of the arteries), serious or
- Congestive heart failure, history of or
- Drug abuse or dependence, history of or
- Glaucoma or
- Heart or blood vessel disease (eg, coronary artery disease), history of or
- Hypertension (high blood pressure) that is not controlled, history of or
- Hyperthyroidism (overactive thyroid) or
- Stroke, history of—Should not be used in patients with these conditions.
- Allergy to tartrazine—Suprenza™ contains tartrazine. Patients with this condition may have an allergic reaction.
- Heart valve disease or
- Hypertension (high blood pressure) or
- Pulmonary hypertension (elevated pressure in the lungs)—Use with caution. May make these conditions worse.
- Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
What is Adipex-P?
Adipex-P (phentermine) is a stimulant similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.
Adipex-P is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Adipex-P may also be used for purposes not listed in this medication guide.
Adipex-P dosing information
Usual Adult Dose for Weight Loss:
18.75 mg to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast. In some cases it may be desirable to give half tablets (18.75 mg) two times a day.
Usual Childrens Dose for Weight Loss:
17 years or older:
18.75 mg to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast. Adipex-P is not recommended for use in pediatric patients under 17 years of age.
For the Consumer
Applies to phentermine: oral capsule, oral capsule extended release, oral tablet, oral tablet disintegrating
Along with its needed effects, phentermine (the active ingredient contained in Adipex-P) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking phentermine:Rare
- Seeing, hearing, or feeling things that are not there
- severe mental changes
- Chest pain
- decreased ability to exercise
- fast, irregular, pounding, or racing heartbeat or pulse
- numbness or tingling in the arms or legs
- swelling of the feet or lower legs
- trembling or shaking of the legs, arms, hands, or feet
- trouble breathing
- trouble with thinking, speaking, or walking
Some side effects of phentermine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Incidence not known
- Decreased interest in sexual intercourse
- difficulty having a bowel movement (stool)
- dry mouth
- false or unusual sense of well-being
- hives or welts, itching, or skin rash
- inability to have or keep an erection
- increased in sexual ability, desire, drive, or performance
- increased interest in sexual intercourse
- loss in sexual ability, desire, drive, or performance
- redness of the skin
- unpleasant taste
For Healthcare Professionals
Applies to phentermine: compounding powder, oral capsule, oral capsule extended release, oral tablet, oral tablet disintegrating
Frequency not reported: Regurgitant cardiac valvular disease, primary pulmonary hypertension, palpitations, tachycardia, elevated blood pressure, precordial pain, ischemic events, angina, myocardial infarction, cardiac failure, cardiac arrest[Ref]
Frequency not reported: Rash[Ref]
Frequency not reported: Dry mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances, nausea, vomiting, abdominal cramps[Ref]
Frequency not reported: Micturition disturbances[Ref]
Frequency not reported: Urticaria[Ref]
Frequency not reported: Overstimulation, restlessness, nervousness, dizziness, euphoria, dysphoria, tremor, headache, fatigue, cerebrovascular events[Ref]
Frequency not reported: Facial edema[Ref]
Frequency not reported: Insomnia, psychosis, impotence, libido changes, depression, hallucinations[Ref]
Some side effects of Adipex-P may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Phentermine Pregnancy Warnings
When administered to animals during late gestation at a dose 7 times the maximum human dose (MHD) on a mg/m2 basis, this drug had no adverse effects on the mothers or offspring; however, a dose 10 times the MRD on a mg/m2 basis abolished estrous cycling. There are no controlled data in human pregnancy. AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage. US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
This drug should not be used during pregnancy; safety during pregnancy has not been established and weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. AU TGA pregnancy category: B2 US FDA pregnancy category: X