Name: Adipost

What should I discuss with my healthcare provider before taking Adipost (phendimetrazine)?

Do not use phendimetrazine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You should not use this medication if you are allergic to phendimetrazine, or if you have:

  • a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, pulmonary hypertension);

  • heart murmur or heart valve disorder;

  • severe or uncontrolled high blood pressure;

  • overactive thyroid;

  • glaucoma;

  • severe agitation or nervousness;

  • if you have a history of drug or alcohol abuse; or

  • if you are allergic to other diet pills, amphetamines, stimulants, or cold medications.

To make sure you can safely take phendimetrazine, tell your doctor if you have any of these other conditions:

  • high blood pressure;

  • kidney disease;

  • diabetes;

  • an anxiety disorder;

  • epilepsy or seizure disorder; or

  • if you have used other diet pills in the past year (prescription, over-the-counter, or herbal products).

Phendimetrazine may be habit forming and should be used only by the person for whom it was prescribed. Never share phendimetrazine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category X. Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use phendimetrazine if you are pregnant. Tell your doctor right away if you become pregnant during treatment.

It is not known whether phendimetrazine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using phendimetrazine.

Phendimetrazine should not be given to a child younger than 17 years old.

Usual Adult Dose for Obesity

-105 mg orally once a day, 30 to 60 minutes before morning meal

-35 mg orally 2 or 3 times a day, one hour before meals
-Maximum dose: 70 mg orally 3 times a day, one hour before meals

-For use as monotherapy only.
-Extended-release: The active drug in each extended release capsule approximates the action of three 35 mg immediate-release doses taken at 4 hour intervals.
-Immediate-release: Dosage should be individualized to obtain an adequate response with the lowest effective dose; 17.5 mg per dose may be adequate in some cases.

Use: Management of exogenous obesity as a short-term adjunct in a regimen of weight reduction based on caloric restriction in patients with
-an initial BMI of 30 kg/m2 or greater OR
-an initial BMI of 27 kg/m2 or greater in the presence of other risk factors (e.g., hypertension, diabetes, hyperlipidemia) who have not responded to appropriate weight reducing regimen (diet and/or exercise) alone.