- Akovaz akovaz dosage
- Akovaz 5 mg
- Akovaz dose range
- Akovaz brand name
- Akovaz dosage
- Akovaz dosage forms
- Akovaz 10 mg
- Akovaz injection
- Akovaz drug
- Akovaz side effects
- Akovaz effects of
The recommended dose range of Akovaz for the treatment of low blood pressure is 5 mg to 10 mg into the vein as needed, not to exceed 50 mg.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Vasopressor
Pharmacologic Class: Adrenergic
Chemical Class: Alkylarylamine
Overdose of ephedrine can cause a rapid rise in blood pressure. In the case of an overdose, careful monitoring of blood pressure is recommended. If blood pressure continues to rise to an unacceptable level, parenteral antihypertensive agents can be administered at the discretion of the clinician.
Carcinogenesis, Mutagenesis, Impairment of Fertility
Carcinogenesis: Two-year feeding studies in rats and mice conducted under the National Toxicology Program (NTP) demonstrated no evidence of carcinogenic potential with ephedrine sulfate at doses up to 10 mg/kg/day and 27 mg/kg/day (approximately 2 times and 3 times the maximum human recommended dose on a mg/m2 basis, respectively).
Mutagenesis: Ephedrine sulfate tested negative in the in vitro bacterial reverse mutation assay, the in vitro mouse lymphoma assay, the in vitro sister chromatid exchange, and the in vitro chromosomal aberration assay.
Impairment of Fertility: Studies to evaluate the effect of ephedrine on fertility have not been conducted.
The evidence for the efficacy of ephedrine injection is derived from the published literature. Increases in blood pressure following administration of ephedrine were observed in 14 studies, including 9 where ephedrine was used in pregnant women undergoing neuraxial anesthesia during Cesarean delivery, 1 study in non-obstetric surgery under neuraxial anesthesia, and 4 studies in patients undergoing surgery under general anesthesia. Ephedrine has been shown to raise systolic and mean blood pressure when administered as a bolus dose following the development of hypotension during anesthesia.
PRINCIPAL DISPLAY PANEL - NDC 76014-005-25 - Alternate 25-count Carton Label (Éclat Pharmaceuticals)
ephedrine sulfate injection
|Labeler - Avadel Legacy Pharmaceuticals, LLC (965538205)|
For the Consumer
Applies to ephedrine: intravenous solution
Along with its needed effects, ephedrine (the active ingredient contained in Akovaz) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ephedrine:Incidence not known
- Blurred vision
- fast, pounding, or irregular heartbeat or pulse
- pounding in the ears
- slow or fast heartbeat
Some side effects of ephedrine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Incidence not known
- Nausea or vomiting