Azelastine-fluticasone Nasal Suspension, Spray

Name: Azelastine-fluticasone Nasal Suspension, Spray

Highlights for azelastine-fluticasone

Azelastine/fluticasone is used to treat symptoms of seasonal nasal allergies. This condition is also called allergic rhinitis.

This is a combination medication. It contains two drugs: azelastine and fluticasone.

Azelastine/fluticasone is available as the brand-name drug Dymista. It’s not available as a generic drug.

Azelastine/fluticasone comes in the form of a nasal spray. It should be sprayed into your nostrils.

Azelastine/fluticasone comes in the form of a nasal spray. It should be sprayed into your nostrils.

The more common side effects of this drug can include nosebleeds, headache, or changes in how things taste.

IMPORTANT INFORMATION
  • Sleepiness See Details

  • Nasal problems See Details

  • Glaucoma and cataracts See Details

  • Slowed growth in children See Details

What is azelastine-fluticasone?

This drug is a prescription drug. It comes in the form of a nasal spray. It should be sprayed into your nostrils.

This drug is a brand-name drug. It’s not available as a generic drug.

This drug is a combination drug. It contains two drugs: azelastine and fluticasone. It’s important to know about both drugs in the combination because each drug may affect you in a different way.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

This drug is used to treat seasonal allergies. It may help improve symptoms such as stuffy or runny nose, itching, or sneezing.

How it works

This drug is a combination of two medications: azelastine and fluticasone. Azelastine belongs to a class of drugs called H1-antagonists. Fluticasone belongs to a class of drugs called corticosteroids.

More Details

Azelastine-fluticasone Side Effects

More Common Side Effects

The more common side effects that can occur with use of azelastine/fluticasone include:

  • nosebleeds

  • headache

  • changes in how things taste

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Extreme sleepiness or drowsiness

  • Nasal problems. Symptoms can include:

    • nosebleeds
    • runny or crusting nose
    • a hole in the cartilage of your nose
  • Slow wound healing in your nose

  • Infections in your nose or throat. Symptoms can include:

    • redness inside your nose or mouth
    • white patches inside your nose or mouth
  • Eye problems such as glaucoma or cataracts. Symptoms can include:

    • changes in your vision
    • a feeling of increased pressure in your eyes
  • Immune system problems. These can cause infections, with symptoms such as:

    • fever
    • muscle aches and pains
    • chills
    • tiredness
  • Low steroid hormone levels in the body. Symptoms can include:

    • feeling tired and weak
    • nausea
    • vomiting
    • low blood pressure
  • Slowed growth in children. Symptoms can include:

    • shorter height than others in age group
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Azelastine-fluticasone May Interact with Other Medications

Azelastine/fluticasone can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Alcohol interaction

Azelastine/fluticasone can make you drowsy and less alert. The use of drinks that contain alcohol while taking this drug can make this problem worse. If you drink alcohol, talk to your doctor about whether taking this drug is safe for you.

Medications that might interact with this drug

Antifungal drugs

When used with azelastine/fluticasone, certain drugs used to treat fungal problems can increase the levels of azelastine/fluticasone in your body. This raises your risk of side effects from azelastine/fluticasone. Examples of these drugs include:

  • ketoconazole
  • itraconazole
  • fluconazole
HIV drugs

Ritonavir is used to treat infection with HIV (human immunodeficiency virus). When used with azelastine/fluticasone, it can increase the levels of azelastine/fluticasone in your body. This raises your risk of side effects from azelastine/fluticasone.

Sleep drugs

When used with azelastine/fluticasone, certain drugs used to help you sleep can cause drowsiness. This may cause problems with daily activities such as driving or working. Examples of these drugs include:

  • eszopiclone
  • zaleplon
  • zolpidem
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Drug warnings

People with nasal problems

This drug may cause nosebleeds, ulcers (sores) in your nose, or holes in your nasal septum (the cartilage between your nasal passages). Before you start taking this drug, tell your doctor about any recent ulcers in your nose, nasal surgery, or injuries to your nose. This drug can make these problems take longer to heal. If you take this drug for several months, you are at risk of infection in your nose.

People with eye problems

This drug may cause glaucoma or cataracts. Your risk is higher if you have a history of eye problems such as increased eye pressure, glaucoma, or cataracts. Your doctor may monitor your vision problems closely while you take this medication.

Pregnant women

This drug is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus.

Women who are breast-feeding

This drug may pass into breast milk and may cause side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your child. You may need to decide whether to stop breast-feeding or stop taking this medication.

For seniors

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

For children

The medication can be used for children ages 6 years and older. This drug is safe for use in children ages 4 and 5 years, but it is not known how well it works for this age group.

The safety and effectiveness of this drug haven’t been established in children younger than 4 years old. This drug should not be used in children younger than 4 years old.

When to call the doctor

Call your doctor if:

  • You accidentally spray this drug into your eyes. First, flush your eyes with water for 10 minutes. Then call your doctor for more instruction.
  • You become pregnant while taking this drug.

Allergies

This drug can cause a severe allergic reaction. Symptoms can include:

  • trouble breathing
  • swelling of the throat or tongue

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

How to Take azelastine-fluticasone (Dosage)

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Nasal allergies

Brand: Dymista

Form: Nasal spray Strengths: 137 mcg azelastine/50 mcg fluticasone in each 0.137 mL spray Adult dosage (ages 18–64 years)
  • Typical dosage: One spray into each nostril twice daily. 
Child dosage (ages 6–17 years)
  • Typical dosage: One spray into each nostril twice daily. 
Child dosage (ages 0–5 years)

The safety and effectiveness of azelastine/fluticasone haven’t been established in children younger than 4 years old. This drug should not be used in people of this age group. Although this drug is safe for children ages 4–5 years, its effectiveness in this age group has not been proven.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you. Important considerations for taking this drug

You can take this drug with or without food

Take this drug at the time(s) recommended by your doctor

Store this drug carefully

See Details

A prescription for this medication is refillable

See Details

Travel

See Details

Self-management

See Details

Clinical monitoring

See Details

Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead.

Insurance

See Details

Are there any alternatives?

(web3)