C1 Inhibitor (Recombinant)
Name: C1 Inhibitor (Recombinant)
- C1 Inhibitor Recombinant side effects
- C1 Inhibitor Recombinant and side effects
- C1 Inhibitor Recombinant drug
- C1 Inhibitor Recombinant adult dose
- C1 Inhibitor Recombinant injection
Hereditary angioedema (HAE): Adolescents: IV: Refer to adult dosing.
Androgens: May enhance the thrombogenic effect of C1 inhibitors. Monitor therapy
Estrogen Derivatives: May enhance the thrombogenic effect of C1 inhibitors. Monitor therapy
Progestins: May enhance the thrombogenic effect of C1 inhibitors. Monitor therapy
• Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)
• Patient may experience diarrhea or nausea. Have patient report immediately to prescriber signs of severe cerebrovascular disease (change in strength on one side is greater than the other, difficulty speaking or thinking, change in balance, or vision changes), severe dizziness, passing out, mouth discoloration, tachycardia, severe headache, or signs of blood clots (numbness or weakness on one side of the body; pain, redness, tenderness, warmth, or swelling in the arms or legs; change in color of an arm or leg; angina; shortness of breath; tachycardia; or coughing up blood) (HCAHPS).
• Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.
Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for healthcare professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience and judgment in diagnosing, treating and advising patients.
Usual Adult Dose for Hereditary Angioedema
Less than 84 kg: 50 international units/kg IV injection once over approximately 5 minutes; may repeat once if symptoms persist.
84 kg or more: 4200 international units IV injection once over approximately 5 minutes; may repeat once if symptoms persist.
Maximum dose: Not to exceed 4200 international units per dose or 2 doses per 24 hours
Liver Dose Adjustments
Data not available
Safety and efficacy have not been established in patients younger than 13 years.
Consult WARNINGS section for additional precautions.