Coenzyme Q10

Name: Coenzyme Q10

What is coenzyme Q10 (ubiquinone, ubidecarenone)-oral, and how does it work (mechanism of action)?

  • Coenzyme Q10 or CoQ10 is naturally produced in the body and is present in the heart, kidney, pancreas, and liver.
  • It is a fat soluble antioxidant and an important chemical used in oxidative respiration for the Krebs cycle and the electron transport chain both of which are critical for the generation of energy that is used by all cells in the body.
  • Coenzyme Q10 levels decrease with age and may be low in people with heart diseases, Parkinson's, disease, cancers, muscular dystrophies, and diabetes.

What are the uses for coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

  • Coenzyme Q10 may be effective for treating coenzyme Q10 deficiency.
  • It is possibly effective for improving vision in people with age-related macular degeneration (AMD or ARMD); improving heart function in people with congestive heart failure; improving symptoms of diabetic neuropathy; improving immune function in people with HIV; reducing blood pressure; reducing the frequency of migraine attacks; and improving physical performance in people with muscular dystrophy.
  • Coenzyme Q10 produced in the laboratory is a component of many herbal products and has many uses.

What are the side effects of coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

The common side effects of coenzyme Q10 are:

  • Stomach upset
  • Decreased appetite
  • Diarrhea
  • Increased levels of liver enzymes in the blood
  • Nausea

Other side effects of coenzyme Q10 include:

  • Allergies
  • Low blood pressure

What is the dosage for coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

  • Doses vary depending on the use. The typical dose for treating coenzyme Q10 deficiency is 150 mg daily.
  • High blood pressure is treated with 120 to 200 mg daily in two divided doses.
  • The dose for preventing migraine headaches is 100 mg three times daily.
  • Doses of 300 to 2400 mg per day have been used for treating Parkinson's disease.

What else should I know about coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

What preparations of coenzyme Q10 (ubiquinone, ubidecarenone)-oral are available?

Soft Gel Tablets: 100 and 300 mg; Capsule: 30, 50, 200, and 400 mg; Gummies: 100 mg

How should I keep coenzyme Q10 (ubiquinone, ubidecarenone)-oral stored?

Coenzyme Q10 should be stored at room temperature 20 C to 25 C (68 F to 77 F).

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Reviewed on 1/13/2016 References Reference: US National Library of Medicine Medline Plus
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