Glasdegib (Oral Route)
Name: Glasdegib (Oral Route)
- Glasdegib Oral Route dosage
- Glasdegib Oral Route dosage forms
- Glasdegib Oral Route side effects
- Glasdegib Oral Route 20 mg
- Glasdegib Oral Route average dose
Glasdegib is used together with low-dose cytarabine to treat newly-diagnosed acute myeloid leukemia (AML) in adults 75 years of age and older or who have other medical conditions that prevent the use of standard chemotherapy. Glasdegib is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of glasdegib in the elderly.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Congestive heart failure or
- Electrolyte imbalance or
- Heart or blood vessel disease, history of—Use with caution. May increase risk for more side effects.
- Heart rhythm problems (eg, long QT syndrome), history of—Use with caution. May make this condition worse.
- Kidney disease, severe or
- Liver disease, moderate to severe—Use has not been studied in patients with these conditions.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- For acute myeloid leukemia:
- Adults—100 milligrams (mg) once a day on Days 1 to 28 (1 cycle) in combination with cytarabine 20 mg injected under the skin 2 times a day on Days 1 to 10 of each cycle. Your doctor may adjust your dose as needed and tolerated.
- Children—Use and dose must be determined by your doctor.
- For acute myeloid leukemia:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.