Granulocyte-Macrophage Colony-Stimulating Factor

Name: Granulocyte-Macrophage Colony-Stimulating Factor

Other uses for this medicine

Sargramostim is also sometimes used to treat certain types of myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells) and aplastic anemia (a condition in which the bone marrow does not produce enough new blood cells). Sargramostim is also sometimes used to decrease the chance of infection in people who have human immunodeficiency virus (HIV). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What side effects can this medication cause?

Sargramostim may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • redness, swelling, bruising, itching or a lump in the area where the medication was injected
  • bone, joint, or muscle pain
  • headache
  • nausea
  • vomiting
  • diarrhea
  • stomach pain
  • mouth sores
  • loss of appetite
  • hair loss

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

  • shortness of breath or fast breathing
  • difficulty breathing
  • wheezing
  • dizziness
  • sweating
  • hives
  • rash
  • itching
  • swelling around the mouth, face, eyes, stomach, feet, ankles, or lower legs
  • sudden weight gain
  • chest pain
  • fast or irregular heartbeat
  • fainting
  • unusual bruising or purple markings under the skin
  • unusual bleeding
  • nosebleeds
  • unusual tiredness or weakness
  • decreased urination

Sargramostim may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, away from sunlight, closed, and out of reach of children. Store sargramostim in the refrigerator. Do not freeze or shake sargramostim. Opened sargramostim vials may be refrigerated for up to 20 days. Dispose of opened vials after 20 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.

Brand names

  • Leukine®