Humalog Mix75/25

Name: Humalog Mix75/25

Why is this medication prescribed?

Insulin lispro is used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). It is also used to treat people with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) who need insulin to control their diabetes. In patients with type 1 diabetes, insulin lispro is always used with another type of insulin, unless it is used in an external insulin pump. In patients with type 2 diabetes, insulin lispro may be used with another type of insulin or with oral medication(s) for diabetes. Insulin lispro is a short-acting, man-made version of human insulin. Insulin lispro works by replacing the insulin that is normally produced by the body and by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What should I do if I forget a dose?

Insulin lispro must be injected shortly before or after a meal. If you remember your dose before or shortly after your meal, inject the missed dose right away. If some time has passed since your meal, follow the instructions provided by your doctor or call your doctor to find out whether you should inject the missed dose. Do not inject a double dose to make up for a missed one.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in and out of reach of children. Store vials of insulin lispro in the refrigerator but do not freeze them. If necessary, you may store the vial you are using outside the refrigerator at room temperature, away from direct heat or sunlight, for up to 28 days. If your doctor tells you to dilute your insulin lispro, the vial of diluted medication can be stored for 28 days in the refrigerator or 14 days at room temperature. Store extra insulin lispro pens and cartridges that are not in use in the refrigerator but do not freeze them. Store the pen and cartridge you are using outside the refrigerator at room temperature for up to 28 days. Store prefilled pens containing Humalog Mix75/25 or Humalog Mix50/50 that are in use outside the refrigerator at room temperature for up to 10 days. Insulin lispro used in an external insulin pump should be thrown away if it is exposed to temperatures over 98.6°F. The temperature of the insulin may be higher than the outside air temperature if the pump housing, cover, tubing, or sport case is exposed to sunlight or direct heat. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Insulin lispro overdose can occur if you use too much insulin lispro or if you use the right amount of insulin lispro but eat less than usual or exercise more than usual. Insulin lispro overdose can cause hypoglycemia. If you have any symptoms of hypoglycemia, follow your doctor's instructions for what you should do if you develop hypoglycemia. Other symptoms of overdose:

  • coma
  • seizures

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to insulin lispro. Your doctor will also tell you how to check your response to insulin lispro by measuring your blood sugar levels at home. Follow these instructions carefully.

You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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