Hydrocortisone, Neomycin, and Polymyxin

Name: Hydrocortisone, Neomycin, and Polymyxin

Why is this medication prescribed?

The combination of hydrocortisone, neomycin, and polymyxin eliminates bacteria that cause ear, eye, and skin infections and relieves pain, inflammation, redness, and itching.

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What should I do if I forget a dose?

Instill or apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill or apply a double dose to make up for a missed one.

What side effects can this medication cause?

Hydrocortisone, neomycin, and polymyxin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  1. itching
  2. burning
  3. pain
  4. swelling
  5. drying or cracking of the skin
  6. acne
  7. change in skin color
  8. blurred vision
  9. hearing difficulty

If you experience any of the following symptoms, call your doctor immediately:

  1. severe skin rash
  2. difficulty breathing or swallowing
  3. wheezing

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Brand names of combination products

  • Cortisporin® (containing Hydrocortisone, Neomycin, Polymyxin B)
  • Oticair® (containing Hydrocortisone, Neomycin, Polymyxin B)
  • Otobione® (containing Hydrocortisone, Neomycin, Polymyxin B)
  • Otocort® (containing Hydrocortisone, Neomycin, Polymyxin B)
  • Pediotic® (containing Hydrocortisone, Neomycin, Polymyxin B)
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