Name: Lipo-Hepin

How should this medicine be used?

Heparin comes as a solution (liquid) to be injected intravenously (into a vein) or deeply under the skin and as a dilute (less concentrated) solution to be injected into intravenous catheters. Heparin should not be injected into a muscle. Heparin is sometimes injected one to six times a day and sometimes given as a slow, continuous injection into the vein. When heparin is used to prevent blood clots from forming in intravenous catheters, it is usually used when the catheter is first put in place, and every time that blood is drawn out of the catheter or medication is given through the catheter.

Heparin may be given to you by a nurse or other healthcare provider, or you may be told to inject the medication by yourself at home. If you will be injecting heparin yourself, a healthcare provider will show you how to inject the medication. Ask your doctor, nurse, or pharmacist if you do not understand these directions or have any questions about where on your body you should inject heparin, how to give the injection, or how to dispose of used needles and syringes after you inject the medication.

If you will be injecting heparin yourself, follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use heparin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Heparin solution comes in different strengths, and using the wrong strength may cause serious problems. Before giving an injection of heparin, check the package label to make sure it is the strength of heparin solution that your doctor prescribed for you. If the strength of heparin is not correct do not use the heparin and call your doctor or pharmacist right away.

Your doctor may increase or decrease your dose during your heparin treatment. If you will be injecting heparin yourself, be sure you know how much medication you should use.

Other uses for this medicine

Heparin is also sometimes used alone or in combination with aspirin to prevent pregnancy loss and other problems in pregnant women who have certain medical conditions and who have experienced these problems in their earlier pregnancies. Talk to your doctor or pharmacist about the risks of using this medication to treat your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What should I do if I forget a dose?

If you will be injecting heparin yourself at home, talk to your doctor about what you should do if you forget to inject a dose.

What side effects can this medication cause?

Heparin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • redness, pain, bruising, or sores at the spot where heparin was injected
  • hair loss

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • unusual bruising or bleeding
  • vomit that is bloody or looks like coffee grounds
  • stool that contains bright red blood or is black and tarry
  • blood in urine
  • excessive tiredness
  • nausea
  • vomiting
  • chest pain, pressure, or squeezing discomfort
  • discomfort in the arms, shoulder, jaw, neck, or back
  • coughing up blood
  • excessive sweating
  • sudden severe headache
  • lightheadedness or fainting
  • sudden loss of balance or coordination
  • sudden trouble walking
  • sudden numbness or weakness of the face, arm or leg, especially on one side of the body
  • sudden confusion, or difficulty speaking or understanding speech
  • difficulty seeing in one or both eyes
  • purple or black skin discoloration
  • pain and blue or dark discoloration in the arms or legs
  • itching and burning, especially on the bottoms of the feet
  • chills
  • fever
  • hives
  • rash
  • wheezing
  • shortness of breath
  • difficulty breathing or swallowing
  • hoarseness
  • painful erection that lasts for hours

Heparin may cause osteoporosis (condition in which the bones become weak and may break easily), especially in people who use the medication for a long time. Talk to your doctor about the risks of using this medication.

Heparin may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • nosebleed
  • blood in urine
  • black, tarry stools
  • easy bruising
  • unusual bleeding
  • red blood in stools
  • vomit that is bloody or looks like coffee grounds

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to heparin. Your doctor may ask you to check your stool for blood using an at-home test.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are using heparin.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.