Nitroglycerin (Transdermal Route)

Name: Nitroglycerin (Transdermal Route)

Canadian Brand Name

  1. Nitrodur 02
  2. Nitro-Dur 02
  3. Nitro-Dur 03
  4. Nitrodur 04
  5. Nitro-Dur 04
  6. Nitrodur 06
  7. Nitro-Dur 06
  8. Nitro-Dur 08
  9. Transderm-Nitro
  10. Trinipatch 02
  11. Trinipatch 04
  12. Trinipatch 06

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of nitroglycerin transdermal in the pediatric population. Safety and efficacy have not been established.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Avanafil
  • Riociguat
  • Sildenafil
  • Tadalafil
  • Vardenafil

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alteplase, Recombinant

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acetylcysteine
  • Aspirin
  • Dihydroergotamine
  • Pancuronium

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Cardioversion (medical heart procedure) or
  • Defibrillation (medical heart procedure)—Use with caution. The patch should be removed before having these procedures.
  • Congestive heart failure or
  • Heart attack, recent or
  • Hypertrophic cardiomyopathy (a heart disease) or
  • Hypotension (low blood pressure) or
  • Hypovolemia (low amount of blood)—Use with caution. May make these conditions worse.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For prevention of angina:
    • For transdermal dosage form (ointment):
      • Adults—At first, 7.5 milligrams (mg), one-half inch of ointment, two times a day. Apply the first dose in the morning right after you wake up, and the second dose 6 hours later. Your doctor may increase your dose as needed.
      • Children—Use and dose must be determined by your doctor.
    • For transdermal dosage form (skin patch):
      • Adults—Apply one patch once a day in the morning. Leave the patch in place for a total of 12 to 14 hours.
      • Children—Use and dose must be determined by your doctor.
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