Probenecid And Colchicine (Oral Route)

Name: Probenecid And Colchicine (Oral Route)


Studies on this combination medicine have been done only in adult patients, and there is no specific information about its use in children.


Elderly people are especially sensitive to the effects of colchicine. This may increase the chance of side effects during treatment.

There is no specific information comparing use of probenecid in the elderly with use in other age groups.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse or
  • Blood disease or
  • Cancer being treated by antineoplastics (cancer medicine) or radiation (x-rays) or
  • Heart disease (severe) or
  • Intestinal disease (severe) or
  • Kidney disease or stones (or history of) or
  • Liver disease or
  • Stomach ulcer or other stomach problems (or history of)—The chance of serious side effects may be increased


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For preventing gout attacks:
      • Adults—One tablet a day for one week, then one tablet twice a day. If you are still having a lot of gout attacks a month after you start taking two tablets a day, your doctor may direct you to increase the dose.
      • Children—Dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.