Siponimod (Oral Route)

Name: Siponimod (Oral Route)

US Brand Name

  1. Mayzent

Descriptions

Siponimod is used to treat the relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. This medicine will not cure MS, but it may slow some of the disabling effects and decrease the number of relapses of the disease.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For relapsing forms of multiple sclerosis:
      • Adults—Dose is based on your genotype and must be determined by your doctor. You will need to take this medicine with a 5-day titration schedule. 0.25 milligram (mg) for Days 1 and 2, 0.5 mg for Day 3, 0.75 mg for Day 4, and 1.25 mg for Day 5 (genotypes *1/*1, *1/*2, or *2/*2). Then, 1mg once a day taken on Day 5 for genotypes *1/*3 or *2/*3 or 2 mg once a day on Day 6 for genotypes *1/*1, *1/*2, or *2/*2.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.

  • If you miss a dose after the initial dose titration, take it as soon as you remember, then go back to your regular dosing schedule.
  • If you miss 1 or more doses during the initial dose titration, you will need to restart the medicine.
  • If you miss a dose for 4 days in a row, you will need to restart the dose titration.
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