Tarka (as a combination product containing Trandolapril, Verapamil)

Name: Tarka (as a combination product containing Trandolapril, Verapamil)

What special precautions should I follow?

Before taking trandolapril and verapamil,

  • tell your doctor and pharmacist if you are allergic to trandolapril, verapamil, benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, or any other drugs.
  • tell your doctor if you have diabetes (high blood sugar) and you are taking aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). Your doctor will probably tell you not to take trandolapril and verapamil if you have diabetes and you are also taking aliskiren.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially albuterol (Volmax, Proventil [tablets and syrup only], Ventolin [tablets and syrup only]); allopurinol (Zyloprim); antacids; betamethasone (Celestone); carbamazepine (Tegretol); chemotherapy medications; cimetidine (Tagamet); cortisone (Cortone); cyclosporine (Neoral, Sandimmune); dantrolene (Dantrium); dexamethasone (Decadron, Dexone); diuretics ('water pills'); fentanyl (Duragesic); fludrocortisone (Florinef); heart and blood pressure medications such as beta-adrenergic blockers, digoxin (Lanoxin), disopyramide (Norpace), flecainide (Tambocor), procainamide (Procan), and quinidine (Quinaglute, Quinadex); hydrocortisone (Cortef, Hydrocortone); lithium (Eskalith, Lithobid); medications that suppress your immune system; medications to treat depression or psychiatric conditions; medications to treat glaucoma (increased pressure in the eye); medications to treat pain; muscle relaxants; methylprednisolone (Medrol); nonsteroidal anti-inflammatory drugs; other medications for high blood pressure or diabetes; phenobarbital; phenytoin (Dilantin); potassium supplements; prednisolone (Prelone); prednisone (Deltasone, Orasone); rifampin (Rifadin, Rimactane); theophylline; tranquilizers; triamcinolone (Aristocort); and vitamins or herbal products.
  • tell your doctor if you have or have ever had heart, liver, or kidney disease; a recent heart attack; an irregular heartbeat; muscular dystrophy; gastrointestinal obstruction (strictures); or diabetes.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking trandolapril and verapamil.
  • you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how trandolapril and verapamil will affect you.
  • remember that alcohol can add to the drowsiness caused by this drug. Do not drink alcohol while taking this medication.

What special dietary instructions should I follow?

Trandolapril and verapamil may cause an upset stomach. Take trandolapril and verapamil with food or milk.Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

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